synthesis of novel heterocyclic system 4h-imidazo [ 2,l -b] pyrido [2,3-el [i, 3,4] thiadigzim
نویسندگان
چکیده
diazotization of 3-amino-2-cmoro pyridine (3) in the presence of dithizone (5) gave dphenyl-2-phenylazo-4h-pyrid[o3 ,2-e] [1,3,4] thiadiazine (6). reaction of 2- chloro-3-nitropyridine (2, g=h) with (5) dfordd 4-phenyl -2-phenylazo -4hpyrido [2,3-el [1,3,4] thiadiazine (7). reduction of the latter with h gas in the presence of raney nickel gave the corresponding amino derivative (12). one pot condensation and cyclization of the latter with phenacyl bromide gave a novel heterocyclic system (13).
منابع مشابه
SYNTHESIS OF NOVEL HETEROCYCLIC SYSTEM 4H-IMIDAZO [ 2,l -b] PYRIDO [2,3-el [I, 3,4] THIADIGZIM
Diazotization of 3-amino-2-cMoro pyridine (3) in the presence of dithizone (5) gave dphenyl-2-phenylazo-4H-pyrid[o3 ,2-e] [1,3,4] thiadiazine (6). Reaction of 2- chloro-3-nitropyridine (2, G=H) with (5) dfordd 4-phenyl -2-phenylazo -4Hpyrido [2,3-el [1,3,4] thiadiazine (7). Reduction of the latter with H gas in the presence of Raney nickel gave the corresponding amino derivative (12). One ...
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3-Mercapto-1,2,4 benzotriazine (1) was methylated by methyl iodide in the presence of base to afford 1,2-dihydro-3-methyhercapto-1, 2,4 benzotriazine (2). The latter was reacted with hydrazine hydrate to give the corresponding 3-hydrazine derivative (3). Compound (3) on condensation with phenacyl bromide gave 3- phenacyl hydrazino l,2,4-benzotriazine (4). PPA cyclization of the ketone (4) ...
متن کاملSYNTHESIS OF OXAZOLO [3, 2-b] 1, 2, 4- TRIAZINES A NOVEL HETEROCYCLIC SYSTEM
The synthesis of 6- methyl- 2- phenyl- 7H- oxazolo [3,2-b] 1,2,4-Triazine- 7-one (6, R=Ph) and its 2-P- bromophenyl analogue to the two members of a new heterocyclic system is described
متن کاملSYNTHESIS OF SOME IMIDAZO [ I , 2-b] [l , 2,4] TRIAZINE AND N-ALKYLATED IMIDAZO [l , 2-b] [1 , 2,4]-TRIAZINES
A number of 3-amino-1, 2, 4-triazin-5 (2H)- ones(1) were synthesized and condensed with a-haloketones to give 2,6-disubstituted imidazo [1, 2-b] [1, 2, 4]-triazin-3 (4H)-ones (2). These compounds were reacted further with a - haloketones to yield N-alkylated products (3).
متن کاملsynthesis of 1,2,4-triazino [3,4-c] [i ,2,4] benzotriazine, a novel heterocyclic system
3-mercapto-1,2,4 benzotriazine (1) was methylated by methyl iodide in the presence of base to afford 1,2-dihydro-3-methyhercapto-1, 2,4 benzotriazine (2). the latter was reacted with hydrazine hydrate to give the corresponding 3-hydrazine derivative (3). compound (3) on condensation with phenacyl bromide gave 3- phenacyl hydrazino l,2,4-benzotriazine (4). ppa cyclization of the ketone (4) yield...
متن کاملChemistry of heterocyclic ketene aminals: construction of imidazo(pyrido)[1,2-a]pyridines and imidazo(pyrido)[3,2,1-ij][1,8]naphthyridines via DABCO-catalyzed tandem annulations.
2-(2-Chloroaroyl)methyleneimidazolidines with four reactive sites show fascinating structural features and could be used as a new strategy for the synthesis of novel heterocycles. This paper presents our new findings in the reaction of 2-(2-chloroaroyl)methyleneimidazolidines with allenic esters affording functionalized imidazo(pyrido)[1,2-a]pyridines via DABCO-catalyzed tandem annulations. Of ...
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عنوان ژورنال:
journal of sciences islamic republic of iranجلد ۹، شماره ۲، صفحات ۰-۰
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